Mesopotamia is a historical region of Western Asia situated within the Tigris-Euphrates river system, in the northern part of the Fertile Crescent, in modern days roughly corresponding to most of Iraq, Kuwait, the eastern parts of Syria, Southeastern Turkey, and regions along the Turkish-Syrian and Iran-Iraq borders. The Sumerians and Akkadians (including Assyrians and Babylonians) dominated Mesopotamia from the beginning of written history (c. 3100 BCE) to the fall of Babylon in 539 BCE, when it was conquered by the Achaemenid Empire. It fell to Alexander the Great in 332 BCE, and after his death, it became part of the Greek Seleucid Empire. Zagros Mountains, Ancient Greek City, Western Asia, Two Rivers, Alexander The Great, Mesopotamia, Ancient Greek, Borders, Map