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Leonardo Da Vinci, Five grotesque heads, (ca 1493), pen and ink; 260 x 205 mm. The Royal Collection / HM Queen Elizabeth II

Leonardo da Vinci in collaboration with GF Rustici (attr.), Horse pace,(1508-1511), bronze; h 156 mm xl 185 mm. Private collection

Leonardo Da Vinci, Codex Atlanticus, 710 recto b, mazzocchio, pen and ink, drilled for dusting; 375 x 154 mm. Milan, and Veneranda Biblioteca Ambrosiana

Leonardo Da Vinci, Bear walking , (first half of 1480), metal tip; 10.3 x 13.3 cm. Lent by The Metropolitan Museum of Art, Robert Lehman Collection, 1975 (1975.1.369)

Leonardo Da Vinci, University of assault chariots armed with scythes, 1482 - 1485 ac, pen and brown ink acquerelato, metal point on paper; 21 x 29.2 cm. Turin Biblioteca Reale (Royal Library)

Attributed to Francesco Colonna (1432-33-c. 1527), Hypnerotomachia Poliphili, 1499, 8vo : π4 a-y8 z10 A-E8 F4 (C1 signed E1) [242 leaves]; RCIN 1057947. Royal Collection Trust / © Her Majesty Queen Elizabeth II 2016

Leaf from a Breviary: The Martyrdom of Saint Denis, about 1467–70. Simon Marmion (Flemish, 1425–1489). Illuminated manuscript: ink, tempera, and gold on vellum; 15.2 x 11.2 cm. The Cleveland Museum of Art, John L. Severance Fund 2005.55

Albrecht Dürer German 1471–1528 Study of a seated youth holding scales 1497 pen and brown ink 24.2 x 20.8 cm (sheet) The State Hermitage Museum, St Petersburg (Inv. no. ОР-16) Acquired from the collection of Count Cobenzl, Brussels, 1768