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Death Most Beautiful Programmed cell death ensures that our bodies contain just the right number of cells. This tightly regulated process removes damaged cells, shapes our organs and digits, and refines our immune systems. Here, multiphoton fluorescence imaging reveals an apoptotic HeLa cell (middle) amongst non-dying neighbors.

2. Crepidula fornicata (slipper limpet) embryo undergoing cleavage from 4 to 8 cells. Confocal image shows DNA in blue (DAPI) and microtubules in yellow (alpha tubulin).

Mouse embryo, day E9.5. Widefield fluorescence image showing immunostaining with anti-Tuj1 (orange) and anti-glucagon (green), counterstained with DAPI (cyan). Eduardo Zattara (University of Maryland, College Park)