If you're coming from Old San Juan (the cruise port) there's a ferry that runs every 15 mins and is $0.50 per person. It will take you across the water to Catano. When you get off the ferry there will be 15 passenger vans a block or 2 away waiting to take you to the distillery at $3 per person. So for $7 round trip you get a couple hours of fun.
"Culebra is a small Caribbean island, mostly covered in nature preserve that lies about 20 miles east of Puerto Rico. You can reach Culebra via daily ferry from Fajardo or on week days from Vieques." Perfect escape between meeting days!