Helping Hands - NICU Preemie caps pattern. from march of dimes website...All babies' skin is delicate but in the NICU that is true times a hundred-fold. The younger the baby the more thin, delicate, and vulnerable their skin. With the very tiniest little Littles, there are places where their is skin is only a few cells deep, so only the softest, most gentle, non-allergenic fibers can be used. Stay away from animal fibers with the exception of alpaca, which is non-allergenic.