Blue People of Kentucky, Appalachia. The genetic form of methemoglobinemia is caused by one of several genetic defects. The Fugates probably had a deficiency in the enzyme called cytochrome-b5 methemoglobin reductase, which is responsible for recessive congenital methemoglobinemia. At levels of between 10 and 20 percent a person can develop blue skin without any other symptoms. Most of blue Fugates never suffered any health effects and lived into their 80s and 90s.
The Atacama Humanoid, is the skeletal remains of a 6-inch (150 mm) human found in a deserted town in the Atacama Desert, Chile in 2003. Ata has since found its way into a private collection in Spain. It was found by Oscar Muñoz near an abandoned church in a ghost town called La Noria, 56 km to the interior of Iquique in northern Chile. Muñoz later sold it to a local pub owner for 30,000 pesos, who then sold it to a Spanish businessman, Ramón Navia-Osorio, who is the current owner.