Alzheimer's

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6y
Your Genome - one-stop-shop of genetics and genomics information
What is Alzheimer's disease? via @yourgenome https://www.yourgenome.org/facts/what-is-alzheimers-disease
Aricept Complexed with Acetylcholinesterase
Aricept Complexed with Acetylcholinesterase - Proteopedia, life in 3D
Acetylcholinesterase
Acetylcholinesterase - Proteopedia, life in 3D
Alzheimer's Disease
Comparison of Normal Brain (Left) & Brain with Alzheimer's (Right)
Solanezumab. An anti-Alzheimer's antibody | Protein Data Bank in Europe
Search the PDB archive ‹ PDBe ‹ EMBL-EBI
5o3o
Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates | PNAS
Fig. 1.
PDB 4e0m structure summary ‹ Protein Data Bank in Europe (PDBe) ‹ EMBL-EBI
<ul class ='image_legend_ul'>The deposited structure of PDB entry 4e0m coloured by chain and viewed from the front. The entry contains: <li class ='image_legend_li'>4 copies of Microtubule-associated protein tau</li><li class ='image_legend_li'>2 non-polymeric entities<ul class ='image_legend_ul'><li class ='image_legend_li'>7 copies of PHOSPHATE ION</li><li class ='image_legend_li'>2 copies of (4S)-2-METHYL-2,4-PENTANEDIOL</li></ul></li>
Cryo-EM structures of tau filaments from Alzheimer’s disease
Structure of tau filaments from Alzheimer's brain.
First atomic structures of Tau filaments from Alzheimer’s disease brain - MRC Laboratory of Molecular Biology
Tau filament structures