Substantia nigra

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Substantia nigra - definition — Neuroscientifically Challenged Oliver Sacks Books, Nursing Pathophysiology, Ventral Tegmental Area, Reticular Activating System, Substantia Nigra, Basal Ganglia, Cranial Nerves, Brain Tissue, Brain Science

Substantia nigra - midbrain nucleus that is rich in dopamine neurons. The substantia nigra supplies the basal ganglia with dopamine, and the death of dopamine neurons here is associated with the symptoms of Parkinson's disease. The substantia nigra is also involved in reward, motivation, and addiction.

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Ventral Tegmental Area, Substantia Nigra, Brain Neuroscience, Behavioral Neuroscience, Nucleus Accumbens, Brain Research, Mental Health Stigma, The Mechanisms, Limbic System

Scientists have laid bare a novel molecular mechanism responsible for the major depression symptom, anhedonia, the loss of the ability to experience pleasure. The brain circuit involved in this newly elucidated pathway is largely identical between rodents and humans, upping the odds that the findings point toward new therapies for depression and other disorders. Additionally, opinion leaders hailed the study’s inventive methodology, saying it may offer a much sounder approach to testing new…

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