Researchers at UT Southwestern Medical Center have uncovered how the body’s inflammatory response can alter how estrogen promotes the growth of breast cancer cells. The researchers have identified how a combination of signaling molecules inhibits the growth of breast cancer cells, improving clinical outcomes for some subtypes of breast cancers. The opensource study is published in Molecular Cell.
@pascalmeier74 Low-oxygen environment leads to heart regeneration in mice research shows Normal, healthy heart muscle is well-supplied with oxygen-rich blood. But UT Southwestern Medical Center cardiologists have been able to regenerate heart muscle by placing mice in an extremely low-oxygen environment. Researchers with the Hamon Center for Regenerative Science and Medicine gradually lowered the oxygen in the air breathed by mice until it was at ...
A team of researchers form the UT Southwestern Medical Center and University of Tsukuba have identified key cells within the brain that are critical for determining circadian rhythms, the 24-hour processes that control sleep and wake cycles, as well as other important body functions such as hormone production, metabolism, and blood pressure. Circadian rhythms are generated by the suprachiasmatic nucleus (SCN) located within the hypothalamus of the brain, but researchers had previously been…
Individuals with amnestic mild cognitive impairment (aMCI) are at twice the risk of others in their age group of progressing to Alzheimer’s disease. Currently there is no conclusive test that exists to predict who will develop Alzheimer’s. Now, research from The University of Texas, University of Illinois, UT Southwestern and John Hopkins University is attempting to identify a potential biomarker that could offer a more complete picture of who is most at risk.
Researchers from UT Southwestern have gleaned a key cellular mechanism of how the body adjusts glucose levels, an important process that when abnormal can promote diabetes, cancer, and rare genetic diseases. The researchers determined that an enzyme called Protein Kinase C (PKC) can regulate whether more or less glucose should be transported into cells, serving as a kind of thermostat to ensure that proper levels are maintained.
Your brain on cannabis: Clearest picture yet of marijuana receptors
The high-resolution structure of the human cannabinoid receptor 1 (CB1) and its binding site for the chemical tetrahydrocannabinol (THC) should lead to a better understanding of how marijuana affects the brain, researchers at UT Southwestern Medical Center say.