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Blood Tests for Prion Disease. Two studies describe methods for detecting these misfolded proteins in human blood samples. Thousands of Europeans may be asymptomatic carriers of variant Creutzfeldt-Jakob disease (vCJD) a fatal prion disease that is the human variant of Mad Cow disease. But now two studies published December 21 in Science Translational Medicine describe new methods for detecting even latent vCJD which could make blood transfusions safer and help early detection and…

Detection of prions in the plasma of presymptomatic and symptomatic patients with variant Creutzfeldt-Jakob disease | Science Translational Medicine

This looks awesome! Syed Z, Stultz CM, Scirica BM, and Guttag JV. 2011. Computationally Generated Cardiac Biomarkers for Risk Stratification After Acute Coronary Syndrome. Sci Transl Med. 3(102):95

A study in this week's Science Translational Medicine is a classic example of how seemingly unlikely collaborators can come together to make surprising discoveries. An international team of gastroenterologists, pediatricians, natural products chemists, and veterinarians, working with zebrafish models ...

ALZHEIMER’S DISEASE Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’s disease mouse model

Lymphoma & Myeloma 2015 Congress Offers Research And Translational Medicine Updates Lymphoma News Today

In Vivo–Directed Evolution of a New Adeno-Associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous. "...A resulting AAV variant mediated widespread delivery to the outer retina and rescued the disease phenotypes of X-linked retinoschisis and Leber’s congenital amaurosis in corresponding mouse models."

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After Zika Infection, People Should Wait Months to Conceive Children, CDC Says

Outbreaks of the Zika virus are likely to occur in the United States; so to prepare, health officials are developing plans to combat Zika that focus on protecting pregnant women from the virus.

Photoactivation of Endogenous Latent Transforming Growth Factor–β1 Directs Dental Stem Cell Differentiation for Regeneration | Science Translational Medicine

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Researchers have harnessed the CRISPR-Cas9 technology to correct mutations in the blood stem cells of patients with a rare immunodeficiency disorder; the engineered cells successfully engrafted in mice for up to five months. Credit: Chris Bickel / Science Translational Medicine (2017)