Osteogenesis Imperfecta Foundation. Also known as “Brittle Bone Disease,” OI is characterized by varying degrees of collagen production impairment. Milder forms of this condition often goes undiagnosed and is mistaken for child abuse as the primary manifestation is multiple fractures, often seen in various phases of healing.
Osteogenesis imperfecta — Medlibes: Online Medical Library Blue sclerae Bone fractures Hyper flexibility Genetic, dominant neg, defect in Type 1 collagen (type ONE = bONE). Usually a gly is mutated and strong tight collagen chain can't form.