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The zebra stripe sign occurs where children with osteogenesis imperfecta have been treated with cyclical bisphosphonate therapy, e.g. pamidronate. When the drug is delivered in cycles, dense bone is formed while treatment is being given. This results in dense stripes across the metaphyses of bones which can be visualized radiographically.

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Atticus Shaffer of TV's "The Middle" Has Osteogenesis Imperfecta

Omg he is by far my favorite actor and of course the greatest character of all of television!

A nursing student who beat the odds

Story of a nursing student with osteogenesis imperfecta. If she can do it, I can quit my whining and do it too!

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Fibromyalgia,, RA, Lupus, and OI, (Osteogenesis Imperfecta). Just a few of many Chronic Pain Issues that we deal with every hour.... Every day. stay strong... STAY STRONG!

FYI: If you would like to learn more about Osteogensis Imperfecta, use the link to visit the Osteogenesis Imperfecta Foundation website.

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Exercising and working out can be daunting when you have Osteogenesis Imperfecta (aka Brittle Bones), but don’t count it out! Physical activity is important for those of us with O.I. and havi…