I våken tilstand skvetter vi til når orienteringsaktivering følges av akutt noradrenerg fyring. I REM søvn er noradrenerge celler i locus coeruleus aktivt inhibert og fyrer ikke. Dopaminerge celler i substantia nigra/ventrale tegmentum fyrer innenfor gammaspekteret både i REM og våken tilstand. Den særegne balansen mellom noradrenerg og dopaminerg aktivitet i REM kan være forklaringen på hvorfor vi ikke "skvetter" i søvne og ved drømme-orientering.

I våken tilstand skvetter vi til når orienteringsaktivering følges av akutt noradrenerg fyring. I REM søvn er noradrenerge celler i locus coeruleus aktivt inhibert og fyrer ikke. Dopaminerge celler i substantia nigra/ventrale tegmentum fyrer innenfor gammaspekteret både i REM og våken tilstand. Den særegne balansen mellom noradrenerg og dopaminerg aktivitet i REM kan være forklaringen på hvorfor vi ikke "skvetter" i søvne og ved drømme-orientering.

Amygdalar Gating of Early Sensory Processing through Interactions with Locus Coeruleus | Journal of Neuroscience

Amygdalar Gating of Early Sensory Processing through Interactions with Locus Coeruleus | Journal of Neuroscience

Midbrain Activation  The periaqueductal grey and locus coeruleus conjointly act with another major half of the brain attached worry, anxiety, and panic attacks-the midbrain.

Midbrain Activation

Midbrain Activation The periaqueductal grey and locus coeruleus conjointly act with another major half of the brain attached worry, anxiety, and panic attacks-the midbrain.

Image result for locus coeruleus

Image result for locus coeruleus

Image result for locus coeruleus

Image result for locus coeruleus

Locus coeruleus. Rhomboid fossa. (Locus coeruleus not labeled, but is very near [just lateral to] colliculus facialis, which is labeled at center left.)

Locus coeruleus. Rhomboid fossa. (Locus coeruleus not labeled, but is very near [just lateral to] colliculus facialis, which is labeled at center left.)

The Big Bang Theory - Fat Jokes About The Locus Coeruleus - Refrigerator Magnet @ niftywarehouse.com #NiftyWarehouse #BigBangTheory #TV #Show #BigBangTheoryShow #BigBangTheoryTVShow #Comedy

The Big Bang Theory - Fat Jokes About The Locus Coeruleus - Refrigerator Magnet @ niftywarehouse.com #NiftyWarehouse #BigBangTheory #TV #Show #BigBangTheoryShow #BigBangTheoryTVShow #Comedy

During acute opiate withdrawal there are usually severe problems with insomnia. This is probably due to a massive rebound activation of brain arousal systems, especially the noradrenaline projections from the locus coeruleus to the cortex. Sleep problems are more prolonged and probably more distressing in people withdrawing from methadone, and there is some evidence that this insomnia is still present at 6 months of abstinence. Sleep disturbance is a powerful predictor of relapse.

During acute opiate withdrawal there are usually severe problems with insomnia. This is probably due to a massive rebound activation of brain arousal systems, especially the noradrenaline projections from the locus coeruleus to the cortex. Sleep problems are more prolonged and probably more distressing in people withdrawing from methadone, and there is some evidence that this insomnia is still present at 6 months of abstinence. Sleep disturbance is a powerful predictor of relapse.

Saatchi Art Artist April Zanne Johnson; Painting, "Locus Coeruleus" #art

Locus Coeruleus

Saatchi Art Artist April Zanne Johnson; Painting, "Locus Coeruleus" #art

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