Sophia has a rare cancer called Langerhans Cell Histiocytosis. She was waiting f...

Sophia has a rare cancer called Langerhans Cell Histiocytosis. She was waiting f...

Vertebra plana or pancake vertebra -  is the term given when a vertebral body has lost almost its entire height anteriorly and posteriorly, representing a very advanced crush fracture. It can occur with a variety of settings, including: trauma, osteoporosis, osteogenesis imperfecta, leukaemia, vertebral metastases  multiple myeloma, Langerhans cell histiocytosis, lymphoma, osteomyelitis, spinal tuberculosis & vertebral haemangioma.

Vertebra plana or pancake vertebra - is the term given when a vertebral body has lost almost its entire height anteriorly and posteriorly, representing a very advanced crush fracture. It can occur with a variety of settings, including: trauma, osteoporosis, osteogenesis imperfecta, leukaemia, vertebral metastases multiple myeloma, Langerhans cell histiocytosis, lymphoma, osteomyelitis, spinal tuberculosis & vertebral haemangioma.

We are Aella's Voice    Aella and Genevieve are one year old identical twins. In July of 2016 Aella who was diagnosed with a very rare type of cancer called systemic Langerhans cell Histiocytosis (LCH). Unfortunately, after being treated for just a short period of time, Aella’s body stopped responding...

We are Aella's Voice Aella and Genevieve are one year old identical twins. In July of 2016 Aella who was diagnosed with a very rare type of cancer called systemic Langerhans cell Histiocytosis (LCH). Unfortunately, after being treated for just a short period of time, Aella’s body stopped responding...

Langerhans cell histiocytosis - very high mag.jpg

Langerhans cell histiocytosis - very high mag.jpg

Langerhans Cell Histiocytosis: Emerging Insights and Clinical Implications | Cancer Network

Langerhans Cell Histiocytosis: Emerging Insights and Clinical Implications | Cancer Network

Langerhans cell histiocytosis - Wikipedia, the free encyclopedia

Langerhans cell histiocytosis - Wikipedia, the free encyclopedia

The skeleton is the most commonly involved organs system in Langerhans cell histiocytosis (LCH) and is by far the most common location for single lesion, often referred to as eosinophilic granuloma (EG) (the terms are used interchangeably in this article). For a general discusion of this disease please refer to the article on Langerhans cell histiocytosis (LCH).   Read more: http://radiopaedia.org/articles/skeletal-manifestations-of-langerhans-cell-histiocytosis

The skeleton is the most commonly involved organs system in Langerhans cell histiocytosis (LCH) and is by far the most common location for single lesion, often referred to as eosinophilic granuloma (EG) (the terms are used interchangeably in this article). For a general discusion of this disease please refer to the article on Langerhans cell histiocytosis (LCH). Read more: http://radiopaedia.org/articles/skeletal-manifestations-of-langerhans-cell-histiocytosis

Dendritic cells are the “shakers and movers" of the immune system. They detect pathogens and then get the immune response rolling by activating T cells. Dendritic cells in the skin and other epithelial surfaces are called Langerhans cells (purple). Like all dendritic cells, Langerhans cells use receptors on their cell surface (e.g., Toll receptors) to identify and uptake pathogens by phagocytosis or endocytosis.

Dendritic cells are the “shakers and movers" of the immune system. They detect pathogens and then get the immune response rolling by activating T cells. Dendritic cells in the skin and other epithelial surfaces are called Langerhans cells (purple). Like all dendritic cells, Langerhans cells use receptors on their cell surface (e.g., Toll receptors) to identify and uptake pathogens by phagocytosis or endocytosis.

Birbeck granules in Langerhans Cell Histiocytosis:    Although  seldom necessary for diagnosis (but as a historical note),  electron microscopy of Langerhans cells demonstrates  pentalaminar rod or disc-shaped, racket-like structures  (Birbeck’s granules).

Birbeck granules in Langerhans Cell Histiocytosis: Although seldom necessary for diagnosis (but as a historical note), electron microscopy of Langerhans cells demonstrates pentalaminar rod or disc-shaped, racket-like structures (Birbeck’s granules).

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