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What a difference a few weeks make Tale of two trials Animal studies get rubbished all the time and one thing that gets peoples backs up is the failure to translate. It is sad when this happens because of the wasted effort and the dashed hopes. As soon as a trial fails however the community view is often very blinkered and it gets the idea that this or that drug is no good and the mud sticks. Therefore animal studies take another bashing. However we do not do enough "trial bashing". I…

Addictions can be substance-related (alcohol, opioids, tobacco) or behavioural (gambling, kleptomania, eating disorders), and when seen in clinic are often a secondary complaint. Addictions can be characterised as an inability to limit the use of a substance or activity, having cravings for these things, an increased tolerance to the abused substance, feelings of withdrawal when attempting to stop, and the substance or activity impairing work and or social responsibility. All of this often…

from That's Natural! CBD Hemp Oil

Research Article From "Neuropharmacology" - Cannabinoids for Anxiety

That's Natural CBD Oil from Hemp - Legal in all 50 States. Research is showing the link between cannabinoids like CBD and the treatment of anxiety and related issues. From the abstract "In conclusion, our findings indicate that CBD could represent a novel fast antidepressant drug, via enhancing both serotonergic and glutamate cortical signalling through a 5-HT1A receptor-dependent mechanism." See more at #natural #health #alternative #wellness #healthy #home #mom #life…

CAPON Binds Nitric Oxide Synthase, Regulating NMDA Receptor–Mediated Glutamate…

from Healthinnovations

Mothers with diabetes more likely to have autism-linked anti-fetal brain autoantibodies.

Newly Identified Gene RANBP1 May Link to Autism and Other Neuro Disorders. This gene belongs to the metabotropic glutamate receptor (mGluR) pathway affecting the neurotransmitter glutamate. Genes in this pathway have also been implicated in subsets of patients with attention-deficit hyperactivity disorder (ADHD) and schizophrenia.

from Healthinnovations

Study identifies microtubule protein crucial for synaptic plasticity and memory.

NMDA glutamate receptors, which function as receptors that bond with glutamates, are known to be deeply involved in memory and learning. In order for memories to be created inside the brain, these NMDA glutamate receptors must first be transported to the synapses.  Now, a study from researchers at the University of Tsukuba and the University…


Cholinesterase inhibitors work by reducing the breakdown of acetylcholine in the brain, a chemical which helps neurons to communicate.Memantine preferentially blocks excessive extrasynaptic activity of the N-methyl-D-aspartate (NMDA) glutamate receptors i