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image of calcium and glutamate at nerve receptor

from Mail Online

Scientists discover the 'missing link' that triggers Alzheimer’s - and hope findings could lead to drugs that restore memory

Researchers at Yale University have found that blocking a protein called 'metabotropic glutamate receptor 5' could restore memory and learning in the brain.

TAKE THE CHALLENGE! Remove all industrially processed foods and avoid restaurants for 30 days to stop feeding unhealthy craving & addiction cycles fed by hidden sources of free glutamate (MSG).

from Healthinnovations

Mothers with diabetes more likely to have autism-linked anti-fetal brain autoantibodies.

Newly Identified Gene RANBP1 May Link to Autism and Other Neuro Disorders. This gene belongs to the metabotropic glutamate receptor (mGluR) pathway affecting the neurotransmitter glutamate. Genes in this pathway have also been implicated in subsets of patients with attention-deficit hyperactivity disorder (ADHD) and schizophrenia.

Cholinesterase inhibitors work by reducing the breakdown of acetylcholine in the brain, a chemical which helps neurons to communicate.Memantine preferentially blocks excessive extrasynaptic activity of the N-methyl-D-aspartate (NMDA) glutamate receptors i

"Monosodium glutamate (MSG) is a widely used flavor enhancer. It is said to add a 5th flavor to foods, a savoury taste, adding onto the four basic tastes (salt, sweet, sour and bitter). It has many names, ranging from accent and vetsin to ajinomoto. What is so curious about MSG is that it does not act by adding a specific taste of its own (as does salt or sugar), but instead it seems to serve as a stimulant which increases the sensitivity of taste receptors thus "multiplying" the taste of…


'The steady decline in risky choices with age matches a steady decline in dopamine levels. Throughout adult life, dopamine levels fall by up to 10% every decade. Dopamine is a chemical in the brain involved in predicting which actions will lead to rewards, and the researchers previously found that volunteers chose significantly more risky gambles to win more money when given a drug that boosted dopamine levels.' Declining dopamine may explain why older people take fewer risks:

What a difference a few weeks make Tale of two trials Animal studies get rubbished all the time and one thing that gets peoples backs up is the failure to translate. It is sad when this happens because of the wasted effort and the dashed hopes. As soon as a trial fails however the community view is often very blinkered and it gets the idea that this or that drug is no good and the mud sticks. Therefore animal studies take another bashing. However we do not do enough "trial bashing". I…

from Healthinnovations

Study identifies microtubule protein crucial for synaptic plasticity and memory.

NMDA glutamate receptors, which function as receptors that bond with glutamates, are known to be deeply involved in memory and learning. In order for memories to be created inside the brain, these NMDA glutamate receptors must first be transported to the synapses.  Now, a study from researchers at the University of Tsukuba and the University…


Many foods are intentionally manipulated or processed to increase addiction and consumption for food industry profit. I’m sure that comes as no surprise to many of you. However, how foods become addicting and the wide-ranging consequences may not be well understood. For example, many people do not connect how a disorder impacting the brain may be a result of their diet. Many industrially processed foods contain excess levels of chemicals that can over stimulate