Nearly a quarter of advanced lung cancer patients fail to receive epidermal growth factor receptor (EGFR) gene mutation test results before starting treatment, according to a new survey of oncologists in 10 countries.
National Guideline Clearinghouse | Chemotherapy and targeted therapy for women with human epidermal growth factor receptor 2–negative (or unknown) advanced breast cancer: American Society of Clinical Oncology clinical practice guideline.
HER2 stands for human epidermal growth factor receptor 2 and is most often seen as HER2. It's a cell protein that stimulates cancer cells to grow. Its presence usually indicates an aggressive cancer. (Click the picture to read more.)
An image of a protein called EGFR (epidermal growth factor receptor) in human cells viewed under a microscope. EGFR, which is shown in green, is localized to the cell's membrane. The cell's nucleus is shown in blue.
Epidermal Growth Factor Receptor and Its Applications - The discovery of growth factors won the Nobel Prize in Medicine in 1986, implying their importance. Epidermal growth factor receptor, EGFR, one of such factors, exists on cell surface and is activated by binding of its specific ligands. EGFR is a member of the receptor tyrosine kinase family whose members play a critical role in oncogenesis. Mutations affecting EGFR expression or activity could result in cancers, ...