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In genetics, a chromosome translocation is a chromosome abnormality caused by rearrangement of parts between nonhomologous chromosomes

An unbalanced translocation occurs when a child inherits a chromosome with extra or missing genetic material from a parent with a balanced translocation.

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Balanced Trans location Support Group - This support group is for men & women struggling with a Balanced Translocation (BT) or an Inversion, both of which are chromosomal abnormalities that often lead to battles with infertility, recurrent miscarriage & pregnancy loss.

Chromosomal translocation & associated neoplasms...

Ewing/PNET characteristic t(11;22) (q24;q12) leading to EWS-FLI1 fusion is encountered in 85% of Ewing Sarcoma/PNET cases. The majority of remaining cases (10-15%) demonstrate fusion of the EWS gene with a second member of the ETS family of genes, namely ERG. The EWS-ERG fusion occurs as a result of chromosomal translocation t(21;22)(q22;q12)

Scientists decipher the molecular basis of an as yet incurable leukemia in children - Although intensive research over the least decade has led to significant improvement of the survival rates of children suffering from ALL, a subset of patients still remains resistant to treatment. One such example is a very aggressive and incurable subtype associated with a t(17;19) chromosomal translocation, which occurs due to breakage and aberrant fusion of genetic material in the tumour cells…

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X-Chromosomal Translocation and Segmental Hypopigmentation — NEJM hypomelanosis of Ito

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The chromosomal translocation characteristic of 70 percent of MCL(Mantel Cell Lymphoma) cases occurs between chromosomes 11 and 14 resulting in the overexpression of cyclinD1

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