If a person has Cushing’s disease, it means that a group of abnormal cells has built up in the pituitary gland to form an ACTH-producing pituitary tumor. These abnormal cells produce ACTH, just as normal pituitary gland cells do—only far too much. The excess ACTH travels to adrenal glands. The adrenal glands are then bombarded with signals to produce more and more cortisol. As a result, the adrenal glands continuously secrete too much cortisol.
Basal Serum Cortisol and Adrenocorticotropic Hormone Levels in Patients with Atopic Dermatitis @http://www.omicsonline.org/open-access/basal-serum-cortisol-and-adrenocorticotropic-hormone-levels-in-patients-withatopic-dermatitis-2155-6121-1000236.php?aid=78391